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Vielhauer Lab - Inflammatory Mechanisms in Renal Disease


Bibliography of Prof. Dr. med. Volker Vielhauer

I received my undergraduate medical training in Munich (Technische Universität and LMU), at the

University of Birmingham (UK) and the National Institute of Neurology, London, and qualified as an

MD in 1996. I completed a Residency in Internal Medicine and Fellowships in Nephrology and later

Rheumatology at the LMU Hospital, becoming board-certified in these specialties. Since 2007, I serve

as Consultant Nephrologist at the LMU Hospital. I earned my doctoral degree at the Institute of

Pathology of the LMU in 2000. Subsequently, I pursued a Postdoctoral Research Fellowship at the

Center of Excellence in Vascular Biology at Brigham and Women`s Hospital and Harvard Medical

School, Boston, from 2002 to 2004. After having returned to the LMU Hospital I became a translational

research group leader in the Nephrology Division, received my Habilitation in 2006 and subsequently

progressed to Associate Professor. I am a Senior Lecturer in Nephrology and Rheumatology, and

coordinate all undergraduate Nephrology teaching at the LMU Hospital.

Education and Academic Appointments

2019 Appointment as Associate Professor, Medical Faculty, LMU Munich

2009 Board certificate in Rheumatology 

2007 Board certificate in Nephrology 

2006 German Habilitation (Privatdozent, PD) in Internal Medicine, Medical Faculty, LMU Munich

2005 Board certificate in Internal Medicine 

2000 MD thesis, Medical Faculty, LMU Munich 

1996 MD (Staatsexamen), LMU Munich 

Additional Qualifications, Awards and Activities 

2012 - 2018 Associate Editor, BMC Nephrology

2008 - present Principal Investigator in 20 multicenter clinical phase II and III studies

2005 PRO SCIENTIA Award, Eckardt-Buddecke-Stiftung

Research Focus and Projects

Our Research Focus


My translational research group at the Division of Nephrology works on immune mechanisms of acute and chronic renal injury, with special interests in the role of chemokines and the TNF system in renal inflammation and progression of injury. The function of inflammatory mediators and particularly endogenous inhibitors of inflammation are investigated in cell culture systems and various murine models of renal diseases.

Our Projects

The following aspects are of particular interest to our lab:

List of Publications


A list of all publications from the Vielhauer Lab can be found on pubmed:


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We gratefully acknowledge support for our work from the following funding sources

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Deutsche Forschungsgemeinschaft


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Medizinische Fakultät, LMU

Förderprogramm für Forschung und Lehre (FöFoLe)

The Current Team

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John Hoppe, MD, Postdoctoral Fellow

I studied medicine at the Medical Faculty of the LMU Munich and joined the Vielhauer Lab to perform my medical doctoral thesis within the FöFoLe program from 2012 - 2015. Now, I am a postdoctoral fellow in this lab. 


Wenkai Xia, MD Student

I am a clinician from China and I joined the Vielhauer Lab to perform my medical doctoral thesis at the Medical Faculty of the LMU in 2019, for which I recruited a PhD scholarship. 

The Team
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Anti-inflammatory and nephroprotective functions of atypical chemokine receptors in kidney disease


This project explores further previously identified anti-inflammatory and anti-fibrotic functions of the atypical chemokine receptor 2 (Ackr2) in chronic renal diseases. Utilizing several kidney disease models, we will characterize local and systemic mechanisms by which Ackr2 limits renal inflammation and fibrotic tissue remodeling.


Project-related publications

Vielhauer V, Allam R, Lindenmeyer MT, Cohen CD, Draganovici D, Mandelbaum J, Eltrich N, Nelson PJ, Anders HJ, Pruenster M, Rot A, Schlöndorff D, Segerer S. Efficient renal recruitment of macrophages and T cells in mice lacking the Duffy antigen/receptor for chemokinesAm J Pathol. 2009;175:119-31.

Bideak A, Blaut A, Hoppe JM, Müller MB, Federico G, Eltrich N, Gröne HJ, Locati M, Vielhauer V. The atypical chemokine receptor 2 limits renal inflammation and fibrosis in murine progressive immune complex glomerulonephritisKidney Int. 2018;93:826-41.

Lux M, Blaut A, Eltrich N, Bideak A, Müller MB, Hoppe JM, Gröne HJ, Locati M, Vielhauer V. The atypical chemokine receptor 2 limits progressive fibrosis after acute ischemic kidney injuryAm J Pathol. 2019;189:231-47.

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TNF-mediated inflammation and cell death as therapeutic targets in kidney disease

The pro-inflammatory cytokine TNF contributes to renal inflammation and cell death in many acute and chronic kidney diseases. We previously characterized functions of TNF receptors and TNF subforms in renal disease models and now particularly focus on the therapeutic potential of endogenous inhibitors of intracellular TNF signaling.


Project-related publications

Vielhauer V, Stavrakis G, Mayadas TN. Renal cell-expressed TNF receptor 2, not receptor 1, is essential for the development of glomerulonephritisJ Clin Invest. 2005;115:1199-209.

Taubitz A, Schwarz M, Eltrich N, Lindenmeyer MT, Vielhauer V. Distinct contributions of TNF receptor 1 and 2 to TNF-induced glomerular inflammation in micePLoS One. 2013;8:e68167.

Vielhauer V. Compartment-specific flow cytometry for the analysis of TNF-mediated recruitment and activation of glomerular leukocytes in murine kidneysMethods Mol Biol. 2014;1155:173-86.

Müller MB, Hoppe JM, Bideak A, Lux M, Lindenmeyer MT, Müller S, Eltrich N, Ryffel B, Vielhauer V. Exclusive expression of transmembrane TNF aggravates acute glomerulonephritis despite reduced leukocyte infiltration and inflammationKidney Int. 2019;95:75-93.

List of Publication


Kidney Immunology Laboratory
University Hospital
Ludwig-Maximilians University Munich

Clinical Unit:

Nephrologisches Zentrum

Ziemssenstr. 5, 80336 Munich

Research Unit:

Kidney Immunology Laboratory, Med. IV

Goetherstr. 31, 80336 Munich


BMC - Biomedical Research Center Munich

Medizinische Klinik und Poliklinik IV LMU Munich

University of Florence

University of Cracow

TRR 332 - Collaborative Research Center 332

​TRR 156 - Collaborative Research Center 156

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